Darunavir (TMC114);地瑞那韦;达芦那韦;206361-99-1 Formula:C27H37N3O7S Darunavir is a drug used to treat HIV infection. It is in the protease inhibitor class. Darunavir is an orally-bioavailable non-peptidic inhibitor of human immunodeficiency virus type 1 (HIV-1) protease that selectively inhibits HIV-1 protease enzyme induced cleavage of gag and gag-pol poly-proteins preventing the maturation of virions and also inhibits the dimerization of HIV-1 protease suppressing proteolytic activity and subsequent replication of HIV-1.