Sorafenib Tosylate；甲苯磺酸索拉非尼；475207-59-1

Formula:C28H24ClF3N4O6S

Molecular Weight：637.03

Appearance：White to off-white powder

Purity：99+%

Sorafenib tosylate is a multikinase inhibitor of Raf-1 and B-Raf with IC50 of 6 nM and 22 nM in cell-free assays, respectively. Sorafenib Tosylate inhibits VEGFR-2, VEGFR-3, PDGFR-β, Flt-3 and c-KIT with IC50 of 90 nM, 20 nM, 57 nM, 59 nM and 68 nM, respectively. Sorafenib Tosylate induces autophagy and apoptosis and activates ferroptosis with anti-tumor activity.