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IWP-2;N -(6-Methyl-2-benzothiazolyl)-2-[(3​,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2- d ]pyrim​idin-2-yl)thio]-acetamide
产品型号:CL2213;CAS No:686770-61-6
英文简称:
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IWP-2;IWP-2;686770-61-6

Formula:C22H18N4O2S3

Molecular Weight:466.60

Appearance:white powder

Purity:98+%
IWP-2 is an inhibitor of Wnt processing and secretion with IC50 of 27 nM in a cell-free assay, selective blockage of Porcn-mediated Wnt palmitoylation, does not affect Wnt/β-catenin in general and displays no effect against Wnt-stimulated cellular responses. IWP-2 specifically inhibits CK1δ.