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Doxorubicin hydrochloride;25316-40-9
产品型号:CL1004
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Doxorubicin hydrochloride;盐酸多柔比星,盐酸阿霉素;25316-40-9


Formula:C27H29NO11.HCl

Molecular Weight: 579.98

Appearance:Orange red powder

Purity:98+%

Doxorubicin (Hydroxydaunorubicin) hydrochloride, a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent. Doxorubicin hydrochloride is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC50s of 0.8 μM and 2.67 μM, respectively. Doxorubicin hydrochloride reduces basal phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase. Doxorubicin hydrochloride induces apoptosis and autophagy