Bortezomib；硼替佐米;保特佐米；179324-69-7

Formula:C19H25BN4O4

Molecular Weight：384.24

Appearance：White to off-white solid

Purity：99+%

Bortezomib is a potent 20S proteasome inhibitor with Ki of 0.6 nM. It exhibits favorable selectivity towards tumor cells over normal cells. Bortezomib (PS-341) inhibits NF-κB and induces ERK phosphorylation to suppress cathepsin B and inhibit the catalytic process of autophagy in ovarian cancer and other solid tumors.