Mitoxantrone dihydrochloride；盐酸米托蒽醌；70476-82-3 Formula：C22H30Cl2N4O6

Formula:C22H29ClN4O6.2HCl

Molecular Weight：517.4 

Appearance：Dark blue powder

Purity：98+%

 Mitoxantrone is an anthraquinone that intercalates in DNA and inhibits topoisomerase II (IC50 = 5.3 μM), thus inhibiting cell proliferation. It also inhibits HIV-1 integrase (IC50 = 3.8 μM). Mitoxantrone is exported from cells in an ATP- and glutathione-dependent manner by multidrug resistance protein-1.4 Formulations containing mitoxantrone have been used in the treatment of cancer and multiple sclerosis.