RepSox (E-616452; SJN 2511;ALK5 Inhibitor II)；2-[3-(6-甲基-2-吡啶基)-1H-吡唑-4-基]-1,5-萘啶；CAS:446859-33-2

Formula:C17H13N5

Molecular Weight： 287.32

Appearance：  Light brown to yellow powder

Purity：98+%

RepSox (E-616452; SJN 2511;ALK5 Inhibitor II)；2-[3-(6-甲基-2-吡啶基)-1H-吡唑-4-基]-1,5-萘啶；CAS:446859-33-2 RepSox (E-616452) is a potent and selective transforming growth factor-beta receptor I/activin like kinase 5 (TGF-β-RI/ALK5) inhibitor. RepSox inhibits ALK5 autophosphorylation with an IC50 value of 4 nM. RepSox can be used for the research of obesity and associated metabolic diseases such as type 2 diabetes.