雷公藤红素;南蛇藤素;南蛇藤醇

Product Name:Celastrol(Tripterine)

 
CAS No.:34157-83-0
 
Synonym:NSC70931;Tripterin;(2R,4aS,6aS,6aR,14aS,14bR)-10-Hydroxy-2,4a,6a,6a,9,14a-hexamethyl-11-oxo-1,3,4,5,6,13,14,14b-octahydropicene-2-carboxylic acid
 
Chemical name:(9β,13α,14β,20α)-3-Hydroxy-9,13-dimethy-l-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen--29-oic acid
 
Molecular formula:C29H38O4
 
Molecular weight:450.61 
  
Purity(HPLC): ≥98%

Biological Activity:
Antioxidant and anti-inflammatory agent. Potently inhibits lipid peroxidation in mitochondria and inhibits TNF-α-induced NFκB activation. Also shown to inhibit topoisomerase II activity in vitro (IC50 = 7.41 μM).