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Macitentan CAS:441798-33-0小分子抑制剂
产品型号：C14530
英文简称：
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Product Name:Macitentan
 
CAS No.:441798-33-0
 
Synonym:ACT 064992;ACT-064992;ACT064992;Sulfamide,N-[5-(4-bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-4-pyrimidinyl]-N'-propyl-
 
Chemical name:N-[5-(4-Bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-4-pyrimidinyl]-N'-propylsulfamide
 
Molecular formula:C19H20Br2N6O4S
 
Molecular weight:588.27
  
Purity(HPLC):≥99%

Biological Activity:
Macitentan(ACT064992) is an orally active, non-peptide dual endothelin ETA and ETB receptor antagonist for the potential treatment of idiopathic pulmonary fibrosis and pulmonary arterial hypertension.