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Apremilast CAS:608141-41-9 小分子抑制剂
产品型号：C14559
英文简称：
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Product Name:Apremilast
 
CAS No.:608141-41-9
 
Synonym:CC-10004;CC 10004; Acetamide, N-[2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-; N-{2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-methanesulfonylethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}ethanimidic acid
 
Chemical name:(S)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione; (S)-N-(2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide
 
Molecular formula:C22H24N2O7S
 
Molecular weight:460.5
  
Purity(HPLC):99%+;ee>99%

Biological Activity:
Apremilast(CC10004) is a novel small molecule inhibitor of PDE4 with an IC50 value of 74 nM.