Product Name:CP21R7(CP21)
 
CAS No.:125314-13-8
 
Synonym:CP21
 
Chemical name:3-(3-aminophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione
 
Molecular formula:C19H15N3O2
 
Molecular weight:317.34 
  
Purity(HPLC):≥99%

Biological Activity:
CP21R7 is a potent and selective GSK-3β inhibitor.
CP21R7 can inhibitor enhances the induction of KDR+precursors prior to vascular commitment.Cp21R7 compound induced the highest luciferase activity at a concentration of 3 μ M. Immunofluorescence staining revealed that CP21 significantly increased total levels of intracellular ?-catenin. Activation of WNT signaling via GSK3 inhibition with CP21 induced commitment of hPSCs towards mesoderm.