1-叔丁基-3-(1-萘基)-1H-吡唑并[3,4-d]嘧啶-4-胺

Product Name:1-Naphthyl PP1
 
CAS No.:221243-82-9
 
Synonym:1-NA-PP 1
 
Chemical name:1-(1,1-Dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
 
Molecular formula:C19H19N5
 
Molecular weight:317.39
  
Purity(HPLC):≥98%

Biological Activity:
1-Naphthyl PP1(1-NA-PP 1) is a selective inhibitor of src family kinases v-Src and c-Fyn as well as the tyrosine kinase c-Abl (IC50 values are 1.0, 0.6, 0.6, 18 and 22 μM for v-Src, c-Fyn, c-Abl, CDK2 and CAMK II respectively).