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阿朴棉子酚 (+)-Apogossypol CAS:66389-74-0
产品型号:C17246
英文简称:
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阿朴棉子酚

Product Name:(+)-Apogossypol
 
CAS No.:66389-74-0
 
Synonym:Apogossypol;NSC736630
 
Molecular formula:C28H30O6
 
Molecular weight:462.53
  
Purity(HPLC):≥98%

Biological Activity:
(+)-Apogossypol(Apogossypol; NSC736630) is a potent inhibitor of Bcl-2 family proteins; competing with the BH3 peptide-binding sites on Bcl-2, Bcl-XL, Mcl-1, Bcl-W, and Bcl-B, but not Bfl-1, with IC50s of 0.5 to 2 μM.