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ONO-4059 hydrochloride CAS:1439901-97-9
产品型号：C17067
英文简称：
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Product Name:ONO-4059 hydrochloride
 
CAS No.:1439901-97-9
 
Synonym:ONO-4059 HCl;ONO4059 hydrochloride;ONO 4059 hydrochloride; GS4059 hydrochloride;GS 4059 hydrochloride;GS-4059 hydrochloride
 
Chemical name:(R)-6-amino-9-(1-but-2-ynoylpyrrolidin-3-yl)-7-(4-phenoxyphenyl)-7H-purin-8(9H)-one HCl salt
 
Molecular formula:C25H23ClN6O3
 
Molecular weight:490.94
  
Purity(HPLC):≥98%

Biological Activity:
ONO-4059 is a selective and novel inhibitor of BTK with IC50 2.2 nm, ONO-4059 binds to BTK within B cells, thereby preventing B-cell receptor signaling and impeding B-cell development.