中文名称：鬼臼**; (5R,5aR,8aR,9R)-5R-5,8,8a,9-四氢-9-羟-5-(3,4,5-**氧苯基)呋喃(3',4':6,7)萘并-[2,3-d]-1,3-间二氧杂环烯-6(5aH)-酮
英文名称：Podophyllotoxin
产品别名：Podophyllinic acid lactone; (5R,5aR,8aR,9R)-5,8,8a,9-Tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-furo(3',4':6,7)naphtho[2,3-d]-1,3-dioxol-6(5aH)-one
CAS:518-28-5
分子式：C22H22O8
分子量：414.41
生物活性：
Podophyllotoxin is a potent inhibitor of microtubule assembly and DNA topoisomerase II.
IC50 Value:
Target: Topoisomerase II; Microtubule/Tubulin
Podophyllotoxin, a kind of non-alkaloid toxin lignan extracted from the roots and rhizomes of Podophyllum plant, has been shown to inhibit the growth of various carcinoma cells. Podophyllotoxin is a natural product that inhibits the polymerization of tubulin and has served as a prototype for the development of diverse antitumor agents in clinical use.