所在位置: 首页 > 化合物对照品/标准品 > 其他类化合物对照品
Cariporide/卡立泊来德 CAS:159138-80-4化合物对照品
产品型号：C16477
英文简称：
产品咨询
咨询电话：021-20908456
产品详情
Product Name:Cariporide/卡立泊来德

CAS:159138-80-4

Synonym: N-(Diaminomethylene)-4-isopropyl-3-(methylsulfonyl)benzamide
Molecular Formula:C12H17N3O3S

Molecular Weight:283.35

Appearance: Powder

Purity: ≥98%

Application: An NHE-1 inhibitor that blocks apoptosis in cardiac muscle cells


 Biological activity: 
Cariporide is a NHE-1 (sodium-hydrogen exchanger isoform-1) inhibitor. Rat studies indicate that cariporide blocks apoptosis of cardiac muscle cells. Additional studies show that the compound interacts with and weakens mitochondrial Ca2+ overload and the permeability transition pore (PTP).