所在位置: 首页 > 化合物对照品/标准品 > 多肽研究系列
**多肽 Exenatide Acetate
产品型号：C13656
英文简称：
产品咨询
咨询电话：021-20908456
产品详情

**多肽

英文名：ExenatideAcetate

现货供应**多肽，别名：Extendin-4
Sequence: His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2
分子式：C184H282N50O60S
分子量：4186.6
外观：White powder
纯度：>99%
CAS：141732-76-5
Biological Activity:
Exenatide is an incretin mimic that acts as an agonist at the glucagon-like peptide 1 receptor to enhance insulin secretion in the presence of raised glucose concentrations.  It is a 39-amino-acid peptide an insulin secretagogue with glucoregulatory effects. It displays biological properties similar to human glucagon-like peptide-1 (GLP-1), a regulator of glucose metabolism and insulin secretion. In contrast to DA-3091, which exhibited an HbA1c-lowering effect even at 0.1 mg/kg dose, the median effective exenatide dose [ED50] for Byetta® LAR was reported to be 74 μg, which approximately corresponded to an exenatide dose of 0.2 mg/kg.