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现货供应AZD1152-HQPA(Barasertib)
产品型号:C13349
英文简称:
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Chemical Name: 2-(5-((7-3-(Ethyl(2-hydroxyethyl)amino)propoxy)quinazolin-4-yl)amino)-1H-pyrazol-3-yl)-N-(3-fluorophenyl)acetamide
英文名:AZD1152-HQPA(Barasertib)
分子式:C26H30FN7O3
分子量:507.56
纯度:>99%
CAS:722544-51-6
Biological Activity:
AZD 1152-HQPA is a highly potent and selective inhibitor of Aurora B, with Ki values to be 0.36 (Aurora B) and 1.369 nM (Aurora A) respectively and has a high specificity versus a panel of 50 other kinases. The dihydrogen phosphate prodrug, AZD 1152 (Barasertib), is converted rapidly to active AZD1152-HQPA in plasma.