现货供应L-Biopterin(NSC 339699)/L-生物蝶呤
产品型号:C13803
英文简称:
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Chemical Name: (1'R,2'S)-Biopterin; 2-Amino-4-hydroxy-6-(1,2-dihydroxypropyl)pteridine
别名:6-Biopterin;NSC 339699; L-erythro-Biopterin
英文名:L-Biopterin
分子式:C9H11N5O3
分子量:237.09
外观:pale yellow powder
纯度:>98%
CAS:22150-76-1
Biological Activity:
L-
Biopterin is the oxidized form of tetrahydro-L-biopterin (BH4), a nitric oxide synthase (NOS) cofactor. L-Biopterin can be reduced to BH4 via thioredoxin reductase followed by dihydropteridine reductase or reduced glutathione. It is extremely toxic to human melanocytes in culture (IC50 = 0.2 µM after 48 hrs). L-Biopterin is rarely found under physiological conditions except in the epidermis of patients with the depigmentation disorder Vitiligo.