现货供应Lovastatin/洛伐他汀
产品型号:C13834
英文简称:
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别名: 洛伐司他汀;(S)-2-甲基丁酸-(1S,3S,7S,8S,8aR) 1,2,3,7,8,8a-六氢-3,7-二甲基-8-{2-[(2R,4R)-4-羟基-6-氧代-2-四氢吡喃基]-乙基}-1-酯
化学名称:1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl 2-methylbutanoate
英文名:Lovastatin
分子式:C24H36O5
分子量: 404.54
外观: A white or almost white crystalline powder
纯度: >99%
CAS No: 75330-75-5
Biological Activity:
Isolated from Aspergillus terreus. An inhibitor of hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase. Also shown to inhibit mevalonate synthesis, thus exhibiting antitumor activity against numerous human cancer cells. Has shown to induce apoptosis in ovarian cancer cells, inhibit cell growth in malignant tumors and acts synergistically with other chemotherapeutic agents. Research has also shown inhibition of p21ras activation and MAP Kinase.