别名：N-(2-(7-Methoxynaphth-1-yl)ethyl)acetamide/N-[2-(7-甲氧基萘-1-基)乙基]乙酰胺

英文名：Agomelatine

分子式：C15H17NO2

分子量： 243.3
纯度：  >99%
外观：White or almost white powder

CAS No：138112-76-2
Biological Activity: 
Agomelatine is an antidepressant drug. It is classified as a norepinephrine-dopamine disinhibitor (NDDI) due to its antagonism of the 5-HT_2C receptor. Activation of 5-HT_2C receptors by serotonin inhibits dopamine and norepinephrine release. Antagonism of 5-HT_2C results in an enhancement of DA and NE release and activity of frontocortical dopaminergic and adrenergic pathways. Agomelatine is also a potent agonist at melatonin receptors which makes it the first melatonergic antidepressant.